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November 30, 2025MedicineOpen Access

Clinical pathological analysis of primary small cell neuroendocrine carcinoma of the cervix: A retrospective study

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Authors

PJPu JinGCGu CongyangSHShiyue Huang

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Overview

Retrospective study reveals treatment and prognosis of small cell neuroendocrine carcinoma in four patients, indicating high invasiveness.

Key Points

  • Prognosis of small cell neuroendocrine carcinoma is poor due to its high invasiveness and malignancy risk.
  • In cases analyzed, immunohistochemical staining showed strong positivity for synaptophysin and other markers.
  • Assessment of clinical data highlighted symptoms like irregular vaginal bleeding and lower abdominal pain in patients.
  • Human papillomavirus infection may contribute to the development of this rare cervical tumor.

Cite This Study

Jin et al. (2025) studied this question.

synapsesocial.com/papers/692b944c1d383f2b2a378debhttps://doi.org/10.1097/md.0000000000046168
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Small Cell Neuroendocrine Carcinoma of the Uterine Cervix: A Case Report Highlighting a Rare and Aggressive Tumor2025
  2. 2Clinical outcomes of neuroendocrine carcinoma of the cervix: Retrospective review from a large academic cancer centre2025
  3. 3Complexities in differential diagnosis of poorly differentiated large cell neuroendocrine carcinoma of the cervix: a case report2025
  4. 4Small cell neuroendocrine carcinoma of the cervix: diagnostic challenges and emerging molecular insights <sup>†</sup>2025
  5. 5Clinicopathologic characteristics and prognostic outcomes of surgically treated neuroendocrine cervical carcinoma: A single institution retrospective analysis2025