Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 28, 2025Therapeutic Advances in Medical OncologyOpen Access

Genomics of uterine malignancies and the potential of precision medicine

View Full Paper
Ask AI
Bookmark
Share

Authors

JPJoseph PolidanoAJAndrew JarrattCSClare L. Scott

Discussion

Loading...

Member takes

Overview

Review uncovers molecular profiles and targeted therapies for uterine neoplasms, highlighting precision medicine's promise in treatment.

Key Points

  • Targeted therapies, including HER2-targeted approaches, show promise for uterine malignancies, potentially improving patient outcomes.
  • The review highlights diverse molecular profiles of neoplasms and the need for precision medicine in gynaeoncology.
  • Specific therapies such as trastuzumab deruxtecan and immune checkpoint inhibitors are explored for their transformative potential.
  • Addressing TP53 mutations and utilizing anti-angiogenic strategies may enhance therapeutic strategies for uterine cancers.

Cite This Study

Polidano et al. (2025) studied this question.

synapsesocial.com/papers/6928f126a65b730b9ea7a37ehttps://doi.org/10.1177/17588359251387395
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Precision Medicine for Gastric Cancer: Current Status and Future Directions2025
  2. 2Molecular Pathways and Biomarkers in Endometrial Carcinoma: Paving the Way for Precision Medicine2025
  3. 3Treatment Of Advanced Endometrial Cancer: A Systematic Review Of Efficacy And Safety In Clinical Trials, Molecular-Targeted Therapies And Immunotherapy.2025
  4. 4Mechanisms and Emerging Targeted Therapies of Uterine Serous Carcinoma2025
  5. 5Integrating POLE Mutations and Mismatch Repair Status in Personalized Medicine for Endometrial Cancer2025