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November 8, 2025Alzheimer s & DementiaOpen Access

Shared genes and pathways in dementia: Insights from genome‐wide association studies

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Review reveals shared genetic pathways in dementia, highlighting implications for polygenic risk scores and genetic diversity.

Dementia shows shared genetic pathways and loci, revealing insights into neurodegeneration.
Analysis of genome-wide association studies emphasizes lipid metabolism and immune responses in dementia.
Examining genetic heterogeneity and utilizing polygenic risk scores could improve disease prediction.
Integrating diverse populations may enhance future research and therapeutic strategies in dementia.

Loi et al. (2025) studied this question.

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