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November 1, 2025World Journal of Clinical Pediatrics

Uncovering hidden vitamin D deficiency in overweight children

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Authors

CDChandra Sekhar Devulapalli

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Overview

Review uncovers obesity-related pathophysiology of vitamin D deficiency in children, suggesting personalized interventions may improve health outcomes.

Key Points

  • Vitamin D deficiency in overweight children is linked to obesity-related pathophysiology, complicating conventional assessments.
  • Critical mechanisms include sequestration in adipose tissue and impaired metabolism, affecting serum vitamin D levels.
  • Personalized approaches to adjust vitamin D dosing considering body composition are emerging for effectiveness.
  • The current lack of pediatric-specific clinical trials limits the understanding of high-dose supplementation outcomes.

Cite This Study

Chandra Sekhar Devulapalli (2025) studied this question.

synapsesocial.com/papers/690550001a99e50463de6b16https://doi.org/10.5409/wjcp.v14.i4.110357
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Vitamin D, Childhood Obesity, and Metabolic Risk – A Scoping Review2025
  2. 2Exploring the Interplay Between Vitamin D and Metabolic Parameters in Pediatric Obesity: Toward Early Biomarker Detection2025
  3. 3Association between Calcium, Magnesium and Lipid Levels of Vitamin D Deficiency in Obese Children: A Cross-sectional Descriptive Study2025
  4. 4Vitamin D Deficiency and Its Association with Obesity Among Urban School-Aged Children in Pakistan: A Cross-Sectional Analysis2025
  5. 5Effects of Vitamin D3 Supplementation on Inflammatory Markers in Overweight and Obese Children and Adolescents: A Systematic Review2025 · 1 citations