October 23, 2025BiomedicinesOpen Access

Clinical and Therapeutic Insights into Sepsis: A Retrospective Observational Study of Inflammatory Markers, and Outcomes

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Discussion

Retrospective study links early inflammatory biomarkers in sepsis patients to improved outcomes, suggesting key insights for mortality prediction.

Mortality risk in sepsis patients correlates with inflammatory biomarker levels, especially fibrinogen and NLR.
In patients under 65, significant decreases in biomarkers from T0 to T2 were noted; survivors showed favorable trends.
Observational analysis of 198 sepsis patients in a single center during 2024 highlighted the role of early diagnostics.
Stable or rising NLR and fibrinogen after hospitalization may indicate poor prognosis, especially in older patients.

Lazăr et al. (2025) studied this question.

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Retrospective study links early inflammatory biomarkers in sepsis patients to improved outcomes, suggesting key insights for mortality prediction.