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October 23, 2025Reproductive Medicine and BiologyOpen Access

Investigating the Link Between Intimate Health, Hygiene and Sexual Practices and the Vaginal Microbiome—The INTIMATE Study

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Authors

KMKristina MagoutasAHAlexandra M. HoldcroftMWMelanie Walls

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Overview

Observational analysis demonstrated monogamous women show significant vaginal microbiome differences, indicating hygiene practices affect infections.

Key Points

  • Infections were fewer with regular perineal washing, while recurrent thrush linked to internal washing.
  • Monogamous women had lower L. crispatus and higher L. iners levels, compared to those with multiple partners.
  • Analysis involved vaginal microbiome examination via 16S rRNA gene sequencing in 96 non-pregnant women.
  • Microbial composition varied with menstrual status, highlighting the importance of intimate health practices.

Cite This Study

Magoutas et al. (2025) studied this question.

synapsesocial.com/papers/68f9d6583f378872224924a3https://doi.org/10.1002/rmb2.12685
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Vaginal microbiota correlations to gynecological symptoms, intimate hygiene practices, and background parameters of IVF patients: a cross-sectional study2025
  2. 2Age-related vaginal microecology and infection epidemiology among premenopausal and postmenopausal gynecologic outpatients: a cross-sectional study2025 · 5 citations
  3. 3Taxonomic and functional profiling of the vulvar microbiome indicates variations related to ecological signatures, aging, and health status2025 · 4 citations
  4. 4Differences in Vaginal Microbiota Composition Between Infertile and Fertile Patients: A Prospective Study2025
  5. 5Genital Lichen Sclerosus—The Role of the Vulvar Microbiome2025