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September 12, 2025MedicinaOpen Access

Genital Lichen Sclerosus—The Role of the Vulvar Microbiome

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Authors

SGSandra Jerković GulinLinköping UniversityOAOlivia AlmlöfOSOliver Seifert

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Implication

This investigation uncovers dysbiosis links to lichen sclerosus, highlighting shifts in Lactobacillus and Gardnerella.

Key Points

  • Women with lichen sclerosus show reduced Lactobacillus and increased Porphyromonas compared to controls.
  • Beta diversity analysis indicates significant microbiome composition differences in lichen sclerosus patients (p = 0.022).
  • Differential abundance analysis identified key genera alterations linked to lichen sclerosus pathology.
  • Research suggests a potential role of microbial dysbiosis in lichen sclerosus, warranting further investigation.

Cite This Study

Gulin et al. (2025) studied this question.

synapsesocial.com/papers/68d41ee1713b0b5dfea68211https://doi.org/10.3390/medicina61091632
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