Global Trends and Scientific Contributions in Thalassemia Research (2015–2024): An Integrative Bibliometric and Meta-Analysis of Diagnostic, Genetic and Treatment Approaches

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Meta-analysis finds CRISPR-Cas9 linked to improved outcomes in thalassemia management, while gene therapy also shows promise for better prognosis.
Bibliometric mapping reveals research peaks in 2016 and 2018, followed by a significant decline in 2024, indicating a need for strategic funding.
Central contributors to thalassemia research include Germany, the US, and India, emphasizing the role of international collaboration.
Diagnostic methodologies exhibit high reliability, with pooled odds ratios of 5.31 for effective platforms like high-performance liquid chromatography.

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Bibliometric analysis shows advancements in thalassemia diagnosis and treatment, highlighting collaboration across nations.

Samanta et al. (2025) studied this question.

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