August 16, 2025Annals of HematologyOpen Access

Beyond transfusions and transplants: genomic innovations rewriting the narrative of thalassemia

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Discussion

Review outlines advancements in gene therapy and genetic testing for thalassemia, highlighting clinical implications.

Advancements in gene therapy show promise in managing thalassemia, shifting from traditional treatments.
Preliminary trials indicate gene editing approaches improve hemoglobin expression, potentially reversing complications.
Observational analysis of interventions demonstrates significant efficacy against treatment-related challenges.
This review underscores the need for genetic testing in primary prevention, aiming to lower disease burden.

Shi et al. (2025) studied this question.

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