October 12, 2025Open Access

Detection of Genetic Biomarkers of Dental Pulp Stem Cell–Mediated Bone Regeneration Using RUNX2 in a Rat Mandibular Defect Model

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RUNX2 overexpression improves bone volume and strength in mandibular defects.
DPSCs significantly promote bone formation, as shown by various assessment techniques.
Transduced DPSCs using revised methods were evaluated for osteogenic potential in vivo.
Genetically enhanced DPSC therapy may lead to personalized treatment for mandibular defects.

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Implication

This research demonstrates RUNX2's impact on bone regeneration in a rat model using dental pulp stem cells, suggesting potential for advanced therapies.

Cite This Study

Bilal et al. (2025) studied this question.

synapsesocial.com/papers/68ebc91af2c3e4d8d926e350 https://doi.org/10.20944/preprints202510.0387.v1

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Implication

This research demonstrates RUNX2's impact on bone regeneration in a rat model using dental pulp stem cells, suggesting potential for advanced therapies.

Detection of Genetic Biomarkers of Dental Pulp Stem Cell–Mediated Bone Regeneration Using RUNX2 in a Rat Mandibular Defect Model

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Discussion

Implication

Cite This Study

Detection of Genetic Biomarkers of Dental Pulp Stem Cell–Mediated Bone Regeneration Using RUNX2 in a Rat Mandibular Defect Model

Key Points

Discussion

Implication

Cite This Study

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