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October 11, 2025Journal of Oncology Pharmacy PracticeOpen Access

An evaluation of a real-world, multi-disciplinary, treatment-free remission programme for patients with Chronic Myeloid Leukaemia

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Authors

EJEleanor JonesJEJoanne EwingHHHayder Hussein

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Overview

Retrospective cohort study found 70.3% success in treatment-free remission for CML patients, suggesting effective multidisciplinary support.

Key Points

  • Overall success rate of achieving treatment-free remission was 70.3% for patients with chronic myeloid leukaemia in the study.
  • Patients meeting international TFR eligibility guidelines had a higher success rate of 77% compared to 55% for those who did not.
  • A retrospective cohort study collected data on patients attempting TFR from January 2016 to August 2024 in a UK centre.
  • Multidisciplinary monitoring ensured that follow-up requirements were met for almost all participants, demonstrating effectiveness.

Cite This Study

Jones et al. (2025) studied this question.

synapsesocial.com/papers/68e9b1d9ba7d64b6fc132d55https://doi.org/10.1177/10781552251384611
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Real-World Evidence-Based Study on Treatment-Free Remission in Chronic Myeloid Leukemia2026
  2. 2TKI Use and Treatment-Free Remission in Chronic Myeloid Leukemia: Evidence from a Regional Cohort Study in the Canary Islands2025
  3. 3Predictors of successful tirosine kinase inhibitor discontinuation in chronic myeloid leukemia: Long-term, real-world evidence on the role of faster molecular decline and duration of response2025
  4. 4Frontline tyrosine kinase inhibitor selection influences eventual treatment-free remission eligibility and sustained treatment-free remission: A registry analysis of patients treated at CML referral sites in Australia2025
  5. 5Predictive factors for successful treatment-free remission in patients with chronic myeloid leukemia: A pooled analysis2025