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October 10, 2025Biological and Clinical Sciences Research Journal

A Randomized Controlled Trial Comparing the Efficacy of the Delayed Absorbable Polydiaxanone (PDS) Versus Non-Absorbable Polypropylene Sutures for Abdominal Wall Closure Following Midline Laparotomies

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Authors

HAHira AsifMAMashya AbbassiMQM. S. Qureshi

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Overview

This randomized controlled trial compares outcomes of polydiaxanone and polypropylene sutures in abdominal wall closure, showing significant benefits of PDS.

Key Points

  • PDS sutures reduced wound dehiscence to 3.0% compared to 10.0% in polypropylene sutures, demonstrating improved efficacy.
  • Surgical site infections were significantly lower in the PDS group (p = 0.03), indicating better wound management.
  • Postoperative pain scores improved at 7 and 14 days for the PDS group (p = 0.02), highlighting its patient-friendly nature.
  • Length of hospital stay showed no significant difference, supporting PDS's effectiveness without prolonged recovery.

Cite This Study

Asif et al. (2025) studied this question.

synapsesocial.com/papers/68e8619c7ef2f04ca37e4296https://doi.org/10.54112/bcsrj.v6i5.1948
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Polypropylene (Prolene) Versus Polydioxanone(Pds) In Abdominal Wall Closure After Laparotomy2025
  2. 2OUTCOME OF PRIMARY VERSUS SECONDARY CLOSURE OF MIDLINE LAPAROTOMY WOUNDS IN PATIENTS WITH PERITONITIS SECONDARY TO ILEAL PERFORATION2025
  3. 3Postoperative pain and wound complications in pediatric transverse laparotomy: mass closure versus layered closure-a randomized clinical trial2025
  4. 4Comparison of Superficial Surgical-Site Infection Rates between Primary and Delayed Primary Wound Closure in Open Appendectomy for Gangrenous or Perforated Appendicitis2023
  5. 5Rectus diastasis repair with and without mesh at 1 year: randomized clinical trial2025 · 2 citations