July 1, 2025

Outcome of Primary Versus Secondary Closure of Midline Laparotomy Wounds in Patients With Peritonitis Secondary to Ileal Perforation

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Randomized controlled study demonstrates lower surgical site infection and dehiscence rates in delayed primary closure for patients with peritonitis.

Delayed primary closure of midline laparotomy wounds significantly reduces the rate of surgical site infections.
In the study, 36.1% of patients experienced infections with primary closure compared to only 18.6% with delayed primary closure.
Wound healing time was shorter for delayed primary closure at 16.8 days compared to 21.5 days for primary closure.
No significant differences were found in mortality or hospital stay lengths between the two closure methods.

Salih et al. (2025) studied this question.

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July 1, 2025

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Authors

Randomized controlled study demonstrates lower surgical site infection and dehiscence rates in delayed primary closure for patients with peritonitis.

Delayed primary closure of midline laparotomy wounds significantly reduces the rate of surgical site infections.
In the study, 36.1% of patients experienced infections with primary closure compared to only 18.6% with delayed primary closure.
Wound healing time was shorter for delayed primary closure at 16.8 days compared to 21.5 days for primary closure.
No significant differences were found in mortality or hospital stay lengths between the two closure methods.

Salih et al. (2025) studied this question.

View Full Paper

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