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October 8, 2025

The Association Between Markers of Lipid Homeostasis, Inflammation, and Atherosclerosis Index in Patients with Type 2 Diabetes and Coronary Heart Disease Stratified by Glycemic Control: A Cross-Sectional Study.

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Authors

PYPing YangTDTian DaiLJLi Jiang

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Overview

Cross-sectional analysis shows glycemic control impacts lipid levels and inflammation in type 2 diabetes patients with CHD, highlighting cardiovascular risk factors.

Key Points

  • Poor glycemic control in type 2 diabetes patients associates with increased arterial stiffness and dyslipidemia, indicating elevated cardiovascular risk.
  • Increased atherosclerosis index (AI) and coronary stenosis scores observed in patients with poor glycemic control, suggesting critical health implications.
  • Key risk factors for elevated AI include inflammatory markers and lipid profiles, with hs-CRP and HOMA-IR serving as independent predictors.
  • Analysis emphasizes the need for a multifactorial approach to managing cardiovascular risk in high-risk groups like those with type 2 diabetes.

Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/68e6d7971ffa7aa7d63d166ahttps://doi.org/10.2147/jir.s550135
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Coronary artery calcification in Type 2 diabetes mellitus: biochemical and inflammatory insights from the Pakistani Population- a case-control study2026
  2. 2BS14 Characterisation of patterns of glycaemia in patients with type 2 diabetes presenting with acute coronary syndrome (ACS) and its association with high-sensitivity C-reactive protein (CRP)2025
  3. 3Lipid Tetrad Index as a Predictive Marker for Coronary Artery Disease in Type 2 Diabetes Patients2025
  4. 4Association of glycated apolipoprotein A1 and low-density lipoprotein cholesterol levels with coronary disease severity and cardiovascular events in type 2 diabetes2026
  5. 5Diagnostic value of systemic immune-inflammation composite index combined with triglyceride-glucose index in type 2 diabetes patients with coronary heart disease: a retrospective diagnostic model study2026