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October 8, 2025

Onion-Mitochondria Inhibit Lipopolysaccharide-Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function.

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Authors

QXQingbo XuYTYun TengYHYinan Huang

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Overview

Dietary mitochondria enhance macrophage energy metabolism in acute lung injury, indicating therapeutic potential.

Key Points

  • Oral administration of onion-derived mitochondria significantly rescues lung macrophage mitochondrial function.
  • In mice with acute lung injury induced by lipopolysaccharide, respiratory health improves with dietary treatment.
  • Evidence suggests that mitochondrial function modulation can reduce oxidative stress and inflammation in lung cells.
  • Enhancing macrophage energy metabolism could present a novel approach for treating lung injury in humans.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68e6d7971ffa7aa7d63d15abhttps://doi.org/10.1002/advs.202506107
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