October 8, 2025BMC UrologyOpen Access

Clinical outcomes and prognostic factors in patients undergoing radical nephrectomy with lymphadenectomy for pN1 renal cell carcinoma

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Discussion

Retrospective analysis shows poor survival outcomes in patients with pN1 renal cell carcinoma, indicating key prognostic factors.

Patients with pN1 renal cell carcinoma have high rates of postoperative recurrence and metastasis.
Among 112 patients, the 3-year overall survival rate was only 36.8%, indicating poor prognosis.
Multivariate analysis revealed preoperative lymph node enlargement as a significant risk factor for metastasis.
Close monitoring is essential for patients with key adverse factors linked to tumor progression.

Cao et al. (2025) studied this question.

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