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October 8, 2025BioinformationOpen Access

Urinary nephrin - An emerging novel biomarker in early detection of diabetic nephropathy: A review

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Authors

RSRamagiri SateeshKSKurpad Nagaraj Shashidhar

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Overview

This review highlights urinary nephrin’s role in detecting diabetic nephropathy early, suggesting its potential impact on management.

Key Points

  • Early detection of diabetic nephropathy can prevent severe renal complications and preserve kidney function.
  • Urinary nephrin levels may serve as a promising biomarker, indicating renal impairment in diabetic patients.
  • Nephrin acts as a podocyte-specific protein crucial for maintaining the glomerular filtration barrier's integrity.
  • Establishing a biological reference interval for urinary nephrin could standardize detection methods and improve outcomes.

Cite This Study

Sateesh et al. (2025) studied this question.

synapsesocial.com/papers/68e5c1be6950a706b22b560ehttps://doi.org/10.6026/973206300213123
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Potential Biomarkers for Early Detection of Diabetic Nephropathy: A Narrative Review2025
  2. 2Exploring the Proteomic Signature of Diabetic Nephropathy: Implications for Early Diagnosis and Treatment2025 · 4 citations
  3. 3Modern approaches to the management of patients with diabetic nephropathy2025
  4. 4A New Hope for Treating Podocytopathies — Emerging Role of Anti-Nephrin Antibody2026
  5. 5The longitudinal associations of selected Tubular Biomarkers Predict the Risk of Nephropathy Progression in Diabetic Patients: systematic review and meta-analysis2025 · 1 citations