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October 8, 2025BioinformationOpen Access

Retrospective cohort study on long-term anticoagulation therapy for bleeding complications among atrial fibrillation patients

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Authors

MJMelanie S. JoyBCBethamcherla Bala ChandruduMIMohamed Ahmed Ibrahim

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Overview

Retrospective cohort study shows bleeding complications in atrial fibrillation patients on anticoagulants, indicating tailored regimens might reduce risks.

Key Points

  • Bleeding complications occurred more frequently in atrial fibrillation patients with unstable INR values.
  • Major bleeding episodes were linked to the type of anticoagulant, particularly with warfarin compared to DOACs.
  • Patient characteristics also contributed to the likelihood of experiencing bleeding complications.
  • The findings underscore the need for personalized anticoagulation therapy to minimize bleeding risks.

Cite This Study

Joy et al. (2025) studied this question.

synapsesocial.com/papers/68e5c1ba6950a706b22b530dhttps://doi.org/10.6026/973206300213417
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Anticoagulation for Atrial Fibrillation with Intermediate Stroke Risk2026
  2. 2Practical Recommendations for Anticoagulation in Patients With Atrial Fibrillation.2026
  3. 3Consider frailty status and comorbidities when choosing anticoagulant treatment for older patients with atrial fibrillation2026
  4. 4Oral anticoagulants and hepatic decompensation in patients with cirrhosis and atrial fibrillation: observational study2026
  5. 5Direct oral anticoagulants in older patients with atrial fibrillation and comorbidities: frailty, renal impairment, acute or chronic coronary syndromes, and acute stroke2026 · 1 citations