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October 2, 2025Pediatric Emergency Medicine Journal

Diagnostic value of systemic inflammation markers in differentiating complicated and simple parapneumonic effusions in children

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Authors

CACeren AkdagHAHurşit Apa

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Overview

Retrospective analysis evaluates inflammatory biomarkers for distinguishing complicated from simple parapneumonic effusions in children, indicating potential for clinical decision-making.

Key Points

  • Systemic inflammatory markers like ESR and CRP effectively differentiate complicated parapneumonic effusions from simple cases, aiding early clinical decisions.
  • Among 200 pediatric patients, longer symptom duration and hospital stay were noted in complicated parapneumonic effusions, highlighting diagnostic challenges.
  • Inflammatory markers, including white blood cells and neutrophil counts, were higher in complicated cases, suggesting their importance in risk stratification.
  • Receiver operating characteristic curves indicate fair diagnostic performance of ESR and CRP in predicting complicated parapneumonic effusions.

Cite This Study

Akdag et al. (2025) studied this question.

synapsesocial.com/papers/68de6f3f83cbc991d0a22cb9https://doi.org/10.22470/pemj.2025.01382
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnostic value of CRP/Albumin-globulin ratio and monocyte-to-lymphocyte ratio in differentiating parapneumonic effusion types.2025
  2. 2Parapneumonic Effusion Versus Pulmonary Empyema in Children: Analysis of Risk Factors and Laboratory Predictors Through a Single Center Experience2025
  3. 3Diagnostic Accuracy of Presepsin, sMR, and Established Inflammatory Biomarkers in Critically Ill Children with Sepsis or Systemic Inflammatory Response Syndrome2025
  4. 4Diagnostic and prognostic utility of salivary and serum procalcitonin, interleukin-6, and interleukin-10 in pediatric pneumonia: a prospective case-control study2025
  5. 5CLR (CRP to Lymphocytes) Score for Differentiating Simple and Complicated Appendicitis in Pediatric Patients2026