Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 1, 2025Journal of Pain ResearchOpen Access

Bridging Pain and Motoric Cognitive Risk Syndrome: Mediating Effect of Handgrip Strength

View Full Paper
Ask AI
Bookmark
Share

Authors

XZXiaojiang ZhaoYZYingcheng ZhuLHLiang Han

Discussion

Loading...

Member takes

Overview

Cross-sectional study finds pain increases likelihood of motoric cognitive risk syndrome, while handgrip strength indicates protective benefits.

Key Points

  • Pain significantly increases the likelihood of developing motoric cognitive risk syndrome (MCR).
  • Handgrip strength (HGS) is negatively associated with MCR prevalence, reducing likelihood with increases in strength.
  • Mediation analysis shows that HGS explains a substantial portion of the relationship between chronic pain and MCR.
  • Demographic stratification provides insights into how pain and HGS impact MCR in different populations.

Cite This Study

Zhao et al. (2025) studied this question.

synapsesocial.com/papers/68dd9537fe798ba2fc499706https://doi.org/10.2147/jpr.s535444
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Relationship Between Motoric Cognitive Risk Syndrome and All-Cause Mortality in Older People: findings from CHARLS 2011–20232025
  2. 2Relationship between adverse childhood experiences and motoric cognitive risk in Chinese older adults: a nationwide study2026
  3. 3Current status and influencing factors of motor-cognitive risk syndrome in the older rural Chinese population: a cross-sectional study2025 · 2 citations
  4. 4Associations Between Physical Activity Frequency, Handgrip Strength, and Limitations in Activities of Daily Living in Middle-Aged and Older Adults with Widespread Pain: A Cross-Sectional Study Using Data from the SHARE Project2025 · 1 citations
  5. 5Mechanistic exploration of obesity-related indicators and motor cognitive risk syndrome: a mediated effect based on C-reactive protein triglyceride glucose index2025 · 3 citations