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October 1, 2025MedicineOpen Access

Pathogenic mechanisms and treatment advances in proliferative vitreoretinopathy: A review

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Authors

JDJinhui DaiXZXiaorong ZhouHBHaixia Bai

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Overview

Review highlights pathogenesis and treatment strategies for proliferative vitreoretinopathy, indicating surgical risks.

Key Points

  • Proliferative vitreoretinopathy is a leading cause of treatment failure in retinal detachment.
  • Current surgical approaches involve membrane removal, but recurrence rates post-surgery remain a concern.
  • The understanding of PVR's pathogenesis is complex, with no ideal therapeutic options established yet.
  • This review explores various treatment strategies and their implications for managing proliferative vitreoretinopathy.

Cite This Study

Dai et al. (2025) studied this question.

synapsesocial.com/papers/68dd91dafe798ba2fc4991bbhttps://doi.org/10.1097/md.0000000000044804
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Long-Standing Problem of Proliferative Retinopathies: Current Understanding and Critical Cues.2025
  2. 2Single-cell transcriptome combined with genetic tracing reveals a roadmap of fibrosis formation during proliferative vitreoretinopathy2025
  3. 3Evaluation of macular microvascular perfusion and function in primary rhegmatogenous retinal detachment with different grades of proliferative vitreoretinopathy2026
  4. 4Minimally invasive PVR surgery-MIPS2025
  5. 5Persistent avascular retina in eyes with retinopathy of prematurity: A comprehensive review2025