Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
October 1, 2025European Journal of Preventive Cardiology

Effect of Structured Exercise Training on Chronotropic Incompetence in Patients with Heart Failure with preserved Ejection Fraction

View Full Paper
Ask AI
Bookmark
Share

Authors

RNRiwa NasserFVFaro R VerelstSMStephan G. Mueller

Discussion

Loading...

Member takes

Overview

Randomized trial found no changes in chronotropic index in heart failure patients after exercise training, suggesting limited impact of high-intensity and moderate training.

Key Points

  • No significant improvement in chronotropic index was observed after three months of exercise training for patients with HFpEF, highlighting a persistent issue.
  • The study involved 175 participants with HFpEF, 51% of whom exhibited chronotropic incompetence, impacting their exercise capacity.
  • Both high-intensity interval training and moderate continuous training enhanced peak oxygen uptake, but did not affect chronotropic reserve.
  • This indicates that while exercise improves overall capacity, it may not address chronotropic incompetence in this patient population.

Cite This Study

Nasser et al. (2025) studied this question.

synapsesocial.com/papers/68dd89e6fe798ba2fc4980cchttps://doi.org/10.1093/eurjpc/zwaf628
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of different exercise training modalities on patient-reported outcomes in heart failure with reduced and preserved ejection fraction2026
  2. 2When there is no consensus definition: the case of chronotropic incompetence2026
  3. 3Association of Chronotropic Competence With Intraoperative Hypotension and Vasopressor Requirement: A Retrospective Cohort Study2026
  4. 4Effects of eccentric cycling training on aerobic and functional capacity in patients with heart failure: a randomised controlled trial2026
  5. 5Functional capacity improvement in patients with chronic heart failure treated with cardiac resynchronisation therapy is not associated with increased chronotropic reserve2026