October 1, 2025CancersOpen Access

Macrophages—Target and Tool in Tumor Treatment: Insights from Ovarian Cancer

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Macrophages play a dual role in ovarian cancer, acting as both tumor drivers and therapeutic targets.
Targeted approaches like CSF-1/CSF-1R inhibitors aim to manipulate tumor-associated macrophages for better outcomes.
Innovative strategies like Chimeric Antigen Receptor Macrophages and Macrophage–Drug Conjugates enhance therapy efficacy.
Research highlights the need for macrophage-focused interventions to improve cancer treatment outcomes.

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Review demonstrates macrophages as dual actors in ovarian cancer, suggesting novel immunotherapy approaches.

Górczak et al. (2025) studied this question.

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