Acute Oral Toxicity and Histophatological Study of Ethanol Extract and Fractions of Etlingera elatior Flowers in Mice

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Study investigates acute oral toxicity and histopathological effects of Etlingera elatior extracts in mice, suggesting low toxicity levels.

No signs of toxicity or mortality were seen in mice treated with Etlingera elatior extracts.
Mice showed no significant changes in body weight after exposure to various doses of extracts.
Histopathological evaluation indicated mild to severe liver and kidney damage, but without a dose-dependent increase.
The oral lethal dose of Etlingera elatior flowers was determined to be higher than 600 mg/Kg.

Sholihah et al. (2025) studied this question.

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Study investigates acute oral toxicity and histopathological effects of Etlingera elatior extracts in mice, suggesting low toxicity levels.