Medical Plants Aframomum melegueta and Xylopia aethiopica Show Low Toxicity in vitro and in vivo Highlighting their Potential for Therapeutic Applications
Original article evaluates toxicity of hydro-ethanolic extracts from Aframomum melegueta and Xylopia aethiopica, implying safety for therapeutic applications.
Key Points
The study revealed low toxicity of hydro-ethanolic extract fractions from Aframomum melegueta and Xylopia aethiopica.
Cytotoxicity testing showed cell death of less than 5%, indicating minimal harm to cells from the extracts.
Histological analysis displayed inflammatory cells in liver and kidney sections, suggesting a localized response.
Sub-acute toxicity tests demonstrated no significant changes in blood composition or biochemical parameters of rats.