Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 25, 2025World Journal of Clinical OncologyOpen Access

Anatomical distribution of bone metastases in stage IV breast cancer: According to histological subtype

View Full Paper
Ask AI
Bookmark
Share

Authors

DZDavid Shaked ZariRNRostislav NovakOHOr Haviv

Discussion

Loading...

Member takes

Overview

Retrospective cohort study examines the anatomical distribution of bone metastases by histological subtype in adults, highlighting key patterns and survival outcomes.

Key Points

  • Rib metastases were found significantly more in HER2-enriched tumors, indicating distinct patterns in bone metastasis.
  • First and subsequent bone metastases showed anatomical trends, particularly high pelvic involvement in HER2-enriched and luminal B.
  • Survival analyses revealed no significant differences in survival metrics like MFI and OS among different breast cancer subtypes.
  • Histological subtype affected the location of initial metastases but did not translate into differences in fracture risk or survival outcomes.

Cite This Study

Zari et al. (2025) studied this question.

synapsesocial.com/papers/68d5bd72dc445aa9033b0cedhttps://doi.org/10.5306/wjco.v16.i9.110087
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long-term survival outcomes and subtype variations between primary breast cancer and liver metastases in 542 patients with advanced breast cancer: insights from a real-world analysis2025
  2. 2Extensive thoracic vertebral and chest wall metastases as the initial presentation of breast cancer: a case report and literature review2025
  3. 3Survival and Prognostic Determinants after IMRT and 3D Radiotherapy in Metachronus Bone – Only Spinal Metastasis of Breast Cancer: A Prospective Phase II Trial2025
  4. 4Overall survival in metastatic breast cancer patients: Real world data from 1000 patients treated at the NCT Heidelberg between 2014 and 20222025
  5. 5Gastric metastasis arising from invasive ductal and mucinous carcinoma of the breast: a case report and literature review2025 · 2 citations