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August 2, 2025Frontiers in OncologyOpen Access

Extensive thoracic vertebral and chest wall metastases as the initial presentation of breast cancer: a case report and literature review

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Authors

YKYergen N. KenzhegulovDZDaniyar K ZhamoldinВАВ.Г. Алейников

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Overview

Case report reveals thoracic vertebral metastases as initial symptom in breast cancer, highlighting diagnostic challenges.

Key Points

  • Metastatic involvement of the thoracic skeleton can be the first sign of an undiagnosed breast cancer.
  • A 60-year-old woman experienced severe thoracic pain, leading to imaging that detected multiple lytic lesions.
  • A percutaneous vertebral biopsy confirmed undifferentiated carcinoma after imaging identified active breast lesions.
  • This case emphasizes the need for high oncologic suspicion and advanced imaging to ensure timely diagnosis and treatment.

Cite This Study

Kenzhegulov et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d0466https://doi.org/10.3389/fonc.2025.1632700
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