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September 23, 2025ANALES RANMOpen Access

Polypharmacy in the older patient

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Authors

JVJuan Antonio Vargas

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Overview

Systematic review highlights the risks of polypharmacy in elderly patients, suggesting deprescribing may improve therapeutic compliance.

Key Points

  • Polypharmacy can lead to increased adverse effects and hospital admissions in older adults, impacting their quality of life.
  • Research indicates that adequate polypharmacy, supported by evidence-based prescriptions, can be beneficial, while inappropriate medication use must be minimized.
  • Deprescribing interventions in older patients are likely to reduce readmission risks, though their long-term effects on mortality remain uncertain.
  • Active monitoring of medications is essential for evaluating benefit-risk ratios in polymedicated elderly patients.

Cite This Study

Juan Antonio Vargas (2025) studied this question.

synapsesocial.com/papers/68d43ee5713b0b5dfea7ec22https://doi.org/10.32440/ar.2025.142.02.rev06
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Navigating Polypharmacy in Elderly Psychiatric Patients: A Review of the Literature2025
  2. 2Polypharmacy Intervention Studies in Older Adults: Challenges in Proving Benefits in Hard Clinical Outcomes2025 · 3 citations
  3. 3How Do Medication Management Interventions Reduce Polypharmacy- Related Risks In Older Adults With Multiple Chronic Conditions?2025
  4. 4The Process of Polypharmacy Management in Older Adults: A Grounded Theory2025
  5. 5Global prevalence, trends, and dose-response associations of polypharmacy in older adults2026 · 3 citations