September 17, 2025Surgical Case ReportsOpen Access

A Case of T1bN0 Esophageal Squamous Cell Carcinoma That Developed Recurrence 7 Years after Curative Esophagectomy

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Recurrence of esophageal squamous cell carcinoma was detected 7 years after surgery.
Patient initially disease-free at 5 years post-esophagectomy showed rising p53 antibody levels.
Imaging techniques led to the discovery of pleural effusion with cancer cells at 7 years.
Suggests careful follow-up is essential even for early-stage ESCC with vascular involvement.

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Case report of delayed recurrence in a patient with esophageal squamous cell carcinoma, highlighting the importance of continued surveillance.

Shiomi et al. (2025) studied this question.

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Case report of delayed recurrence in a patient with esophageal squamous cell carcinoma, highlighting the importance of continued surveillance.