September 21, 2025

Diagnostic, prognostic, and immune-related roles of G3BP1 in pan-cancer.

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Comprehensive analysis reveals G3BP1 as a potential biomarker in cancer prognosis and immunity.

G3BP1 is highly expressed in most cancers and linked to poor prognosis, showing its potential as a key biomarker.
The analysis revealed G3BP1's early diagnostic value in 10 tumour types, indicating its broad relevance in cancer care.
High G3BP1 expression correlates with an immunosuppressive tumour microenvironment, affecting responses to immunotherapy.
The study also highlighted G3BP1's interactions with genes and chemicals, stressing its complex role in cancer biology.

Lu et al. (2025) studied this question.

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