September 21, 2025The Journal of Tehran University Heart CenterOpen Access

Cardiac Dysfunction in β-Thalassemia: A Narrative Review

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Iron overload critically affects cardiac health, leading to heart failure and arrhythmias in β-thalassemia patients.
Lifelong transfusions exacerbate iron deposition in the heart, resulting in dilated and restrictive cardiomyopathy.
Conventional echocardiography often misses early cardiac dysfunction, necessitating advanced imaging techniques for timely diagnosis.
Regular monitoring and genetic predisposition assessments are vital for early intervention and management of heart complications.

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Implication

This narrative review explores how chronic blood transfusions in β-thalassemia lead to iron overload, worsening cardiac dysfunction and heart failure.

Cite This Study

Jaber et al. (2025) studied this question.

synapsesocial.com/papers/68d43afa713b0b5dfea7ac7f https://doi.org/10.18502/jthc.v20i2.19709

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Implication

This narrative review explores how chronic blood transfusions in β-thalassemia lead to iron overload, worsening cardiac dysfunction and heart failure.

Cardiac Dysfunction in β-Thalassemia: A Narrative Review

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Implication

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Cardiac Dysfunction in β-Thalassemia: A Narrative Review

Key Points

Discussion

Implication

Cite This Study

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