Comparing Fractional Flow Reserve Versus Intravascular Ultrasound for Percutaneous Coronary Intervention Guidance: A Systematic Review and Meta-Analysis

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Discussion

Systematic review evaluates FFR and intravascular ultrasound guidance in PCI, highlighting similar outcomes.

FFR and IVUS showed comparable major adverse cardiovascular event rates in PCI patients, supporting either method.
Outcomes for all-cause mortality were similar between FFR and IVUS guidance in coronary interventions.
Analysis included 5 studies with 4714 patients, ensuring robust comparisons between the two guidance methods.
Cost-efficiency favors FFR, as it can avoid unnecessary interventions while managing coronary lesions effectively.

Cheema et al. (2025) studied this question.

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View Full Paper

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Authors

Systematic review evaluates FFR and intravascular ultrasound guidance in PCI, highlighting similar outcomes.

FFR and IVUS showed comparable major adverse cardiovascular event rates in PCI patients, supporting either method.
Outcomes for all-cause mortality were similar between FFR and IVUS guidance in coronary interventions.
Analysis included 5 studies with 4714 patients, ensuring robust comparisons between the two guidance methods.
Cost-efficiency favors FFR, as it can avoid unnecessary interventions while managing coronary lesions effectively.

Cheema et al. (2025) studied this question.

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