Myocardial Inflammation as Key Mediator of Heart-brain Interaction After Myocardial Ischemia/Infarction: Mechanistic Exploration of Post-Myocardial Infarction Cognitive Dysfunction

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This review explores how myocardial infarction impacts cognitive dysfunction through inflammatory mediators and the blood-brain barrier.

Myocardial infarction triggers inflammatory processes that may affect cognitive function through the brain.
The interaction between heart inflammation and the blood-brain barrier suggests significant implications for patient cognitive health.
Investigating the impact of myocardial-derived mediators on the brain could lead to better cognitive protection strategies.
Elucidating the mechanistic pathways of heart-brain interactions post-infarction may offer new therapeutic opportunities.

Wang et al. (2025) studied this question.

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