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September 19, 2025Cancer Epidemiology Biomarkers & Prevention

Abstract B123: Understanding racial disparities in breast cancer mortality beyond 10 years: The role of estrogen receptor status

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Authors

LCLindsay J. CollinMMMaret L. MaliniakJSJeffrey M. Switchenko

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Overview

Analysis of late breast cancer mortality rates in patients indicates significant racial disparities by estrogen receptor status.

Key Points

  • NHB women are 1.85 times more likely to die from breast cancer compared to NHW women, indicating significant racial disparities.
  • Long-term survivors exhibited a median follow-up of 14.8 years, suggesting prolonged monitoring is necessary for understanding late recurrences.
  • Women with ER− tumors had higher mortality rates than ER+ in the overall cohort, flipping in long-term survivors, spotlighting the complexities of estrogen receptor status.
  • The highest cumulative incidence of late breast cancer mortality was seen in NHB women with ER+ tumors, suggesting targeted interventions may be needed.

Cite This Study

Collin et al. (2025) studied this question.

synapsesocial.com/papers/68d436f6713b0b5dfea76471https://doi.org/10.1158/1538-7755.disp25-b123
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract A076: Using a counterfactual framework to understand the underlying causes of Black-White racial disparities in breast cancer mortality in the US2025
  2. 2Abstract A141: Health disparities among women who received treatment for 1L advanced and recurrent endometrial cancer in the United States2025
  3. 3Abstract A082: Differential expression of transcriptomic pathways contributes to survival disparities between Black and White women with breast cancer2025
  4. 4Abstract B055: Guideline-concordance along the cancer care continuum and breast cancer mortality by race and ethnicity: A SEER-Medicare study2025
  5. 5Abstract A103: The effect of time on historical redlining disparities in breast cancer survival2025