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September 19, 2025Open Access

Diabetes mellitus and its chronic complications

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Authors

RDRenato DiscacciatiABAna Lara Brito BarcelosGSGabriela Ziebert dos Santos

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Overview

This integrative review outlines diabetes mellitus complications, highlighting the roles of inflammation and glycemic control.

Key Points

  • Diabetes mellitus leads to microvascular and macrovascular complications, causing significant health burdens.
  • Findings reveal that oxidative stress and inflammation are key drivers of chronic complications from diabetes.
  • An integrative review across multiple databases assessed outcomes related to diabetes complications from 2015 to 2025.
  • Effective management of diabetes requires more than glycemic control; a multifactorial approach is necessary.

Cite This Study

Discacciati et al. (2025) studied this question.

synapsesocial.com/papers/68d436ef713b0b5dfea761bbhttps://doi.org/10.70164/ihsr.v1i4.53
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Also Consider

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  1. 1Diabetic Comorbidities and its Molecular Mechanism2025
  2. 2Oxidative–Inflammatory Crosstalk and Multi-Target Natural Agents: Decoding Diabetic Vascular Complications2025 · 21 citations
  3. 3A MODERN APPROACH TO THE MANAGEMENT OF TYPE 2 DIABETES MELLITUS COMPLICATED BY DIABETIC FOOT SYNDROME2025
  4. 4Why Diabetes Worsens Patient Prognosis: A Literature Review of Cardiovascular and Renal Complications2025
  5. 5Investigating the Pathological Mechanisms Underlying the Development of Diabetic Complications, Such as Neuropathy, Nephropathy and Retinopathy2023