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September 18, 2025Journal of Sports Sciences

Combined effects of physical activity and diet on chronic inflammation of overweight/obese children and adolescents: A systematic review and meta-analysis

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Authors

CZConstantine ZalagkitisΑPΑnastassios PhilippouEKEleftherios Karatzanos

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Overview

Systematic review and meta-analysis shows combined interventions lower inflammation markers in adolescents, suggesting effective strategies for health improvement.

Key Points

  • Combined physical activity and diet interventions likely reduce C-reactive protein in overweight children and adolescents.
  • Meta-analysis discovered reductions in interleukin-6 and interleukin-1β levels due to intervention strategies.
  • No significant effect was observed for tumor necrosis factor alpha and interleukin-10 in the same population.
  • The systematic review included fifty eligible publications, highlighting the strength of the combined approach in intervention.

Cite This Study

Zalagkitis et al. (2025) studied this question.

synapsesocial.com/papers/68d434e3713b0b5dfea74326https://doi.org/10.1080/02640414.2025.2561349
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