Anti-Obesity Effects and Changes of Fecal Microbiome by Lactic Acid Bacteria from Grains in a High-Fat Diet Mouse Model

View Full Paper

Ask AI

Bookmark

Authors

Discussion

This research reveals that a lactic acid bacteria improves lipid metabolism in mice on a high-fat diet, indicating potential for obesity treatment.

Oral administration of Lactiplantibacillus plantarum RP12 significantly reduced body weight gain and fat mass in obese mice.
Treatment led to a notable decrease in serum cholesterol and triglycerides, highlighting its lipid-lowering potential.
This strain modified fecal microbiota composition while promoting short-chain fatty acids production in high-fat diet mice.
Lactiplantibacillus plantarum RP12 also improved the morphology of the intestine, indicating its protective effects against diet-induced damage.

Jeon et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

This research reveals that a lactic acid bacteria improves lipid metabolism in mice on a high-fat diet, indicating potential for obesity treatment.