Relationship between brain oxygen metabolism and cognition in older adults

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Higher brain oxygen metabolism correlates with lower cognitive function in early Alzheimer's disease.
Cerebral metabolic rate of oxygen was significantly lower in participants with MCI compared to the unimpaired group.
Using non-invasive MRI, we measured brain metabolism and its effect on cognitive test results.
Findings highlight the complex relationship between brain metabolism and cognitive changes during neurodegeneration.

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Analysis shows brain metabolism influences cognitive performance in those with Alzheimer's disease and mild cognitive impairment.

Wu et al. (2025) studied this question.

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