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September 16, 2025Gut MicrobesOpen Access

Seeding and feeding: nutrition and birth-associated exposures shape gut microbiome assembly in breastfed infants

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Authors

LSLisa F. StinsonINIsabella NorrishFMFaith Mhembere

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Overview

Analysis reveals gut microbiome structure varies significantly with diet in breastfed infants, suggesting health implications linked to birth mode and nutrition.

Key Points

  • Gut microbiome composition stabilizes between 2 and 5 months in breastfed infants, indicating a critical development window.
  • Introduction of solid foods significantly increases microbiome diversity and reconfigures microbial composition, according to analysis of 698 stool samples.
  • Cesarean delivery affects Bacteroides abundance temporarily, without impacting Bifidobacterium levels, showcasing breastfeeding's protective role.
  • Weaning shows minimal effects on overall microbiota structure but decreases certain Bifidobacterium species, underscoring human milk's sustained influence.

Cite This Study

Stinson et al. (2025) studied this question.

synapsesocial.com/papers/68d42056713b0b5dfea692a5https://doi.org/10.1080/19490976.2025.2557981
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Changes in healthy infant gut microbiota over the past decades2025
  2. 2Longitudinal Profiling of the Human Milk Microbiome from Birth to 12 Months Reveals Overall Stability and Selective Taxa-Level Variation2025
  3. 3Longitudinal profiling of one infant fecal microbiota over the first three years: effects of probiotics and prebiotics2026
  4. 4The Gut Microbiota of Peruvian Children Under the Age of Two During the Complementary Feeding Period2025
  5. 5Establishment of the early gut microbiota in vaginally delivered infants: the influence of maternal gut microbiota outweighs vaginal microbiota.2025 · 7 citations