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August 13, 2025

Establishment of the early gut microbiota in vaginally delivered infants: the influence of maternal gut microbiota outweighs vaginal microbiota.

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Authors

HXHaishan XieLMLulu MengXDXia Duan

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Overview

Research shows maternal gut microbiota shapes gut microbiota in infants born vaginally, indicating its key role in colonization.

Key Points

  • Maternal gut microbiota at 32 weeks significantly influences the gut microbiota of vaginally delivered infants.
  • Vaginal microbiota has minimal impact on the early gut microbiota of infants, contributing less than 1%.
  • Placental microbiota serves as an essential source for the fetal gut microbiota, affecting colonization dynamics.
  • By day 14, infant gut microbiota becomes similar in both vaginally and cesarean-delivered infants post-breastfeeding.

Cite This Study

Xie et al. (2025) studied this question.

synapsesocial.com/papers/689e03efd61984b91e13d655https://doi.org/10.1128/spectrum.01775-25
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