September 13, 2025Cancer Causes & ControlOpen Access

Impact of neighbor-level disadvantage on survival outcomes in head and neck squamous cell carcinoma

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Cohort study shows higher area deprivation index worsens survival outcomes in head and neck cancer patients, suggesting social factors impact health.

Patients with higher area deprivation index scores had significantly lower overall survival rates.
Higher terciles of the area deprivation index showed increased hazards of death and cancer recurrence.
The study included 792 patients diagnosed with untreated head and neck squamous cell carcinoma.
Social determinants of health, including area deprivation index components, are crucial in HNSCC mortality.

Benjamin et al. (2025) studied this question.

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Cohort study shows higher area deprivation index worsens survival outcomes in head and neck cancer patients, suggesting social factors impact health.