Comparative study to evaluate the anti-diabetic and anti-bacterial potential of Tinospora cordifolia and Catharanthus roseus plant extracts

Tinospora cordifolia (Giloy) and Catharanthus roseus (Sadabahar) possess an abundance of bioactive substances and other advantageous attributes. Methanolic extracts of the entire plant from both plants were examined in the in vitro investigation for their anti-bacterial and anti-diabetic properties. The results of the anti-bacterial activity demonstrated that the methanolic plants extract had anti-bacterial activity against Staphylococcus aureus, Escherichia coli and Bacillus subtilis bacteria. In comparison to T. cordifolia, C. roseus showed the maximum zone of inhibition. Extracts from C. roseus exhibit a higher α-amylase inhibitory activity (55.43%) in comparison to extracts from T. cordifolia (53.44%) thus proving higher anti-diabetic potential. The methanolic extract of both plants contained phenols, flavonoids, proteins, carbohydrates and sterols, based on the results of the qualitative analysis of significant secondary metabolites. The current study has therefore concluded that T. cordifolia and C. roseus, two medicinal plants, may aid in the discovery of novel medications that may be used as treatments for bacterial and diabetes ailments that are resistant to current medications.