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September 11, 2025Microbiology & Infectious Diseases

Early versus Late Enteral Prophylactic Iron Supplementation in Preterm Infants: A Randomized Controlled Trial

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Authors

MMMohtarama MostariMKM. KabirAAAbdullahel Amaan

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Overview

Randomized controlled trial compares early and late iron supplementation effects on preterm infants, suggesting significant differences in serum ferritin levels.

Key Points

  • Early iron supplementation significantly increased serum ferritin levels compared to late supplementation.
  • At 12 weeks, mean serum ferritin levels were 92.75 ng/mL in early group versus 56.95 ng/mL in late group, with a p-value of 0.01.
  • The randomized controlled trial included 40 preterm infants in total, assessing various health metrics over 12 weeks.
  • Anthropometric measurements like weight and length did not show significant differences between the two groups by the study's conclusion.

Cite This Study

Mostari et al. (2025) studied this question.

synapsesocial.com/papers/68d41720713b0b5dfea6311ehttps://doi.org/10.33425/2639-9458.1220
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Influence of Intensive Nutritional Education on the Iron Status in Infants—Randomised Controlled Study2025 · 2 citations
  2. 2Iron Supplementation at 1 mg/kg/Day for Exclusively Breastfed Full‐Term Infants: A Meta‐Analysis2025
  3. 3Iron deficiency at neonatal intensive care unit discharge in very preterm infants2025
  4. 4Comparison of Early Vs Late Initiation of Trophic Feeding in Preterm Neonates2025
  5. 5A Randomized Control Trial Comparing the Iron Profile Changes Following Intravenous Ferric Carboxymaltose and Iron Sucrose in the Treatment of Iron Deficiency Anemia in Pregnancy2022