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September 10, 2025BMC Infectious DiseasesOpen Access

Bloodstream infections: trends in etiology and antimicrobial resistance in 10 years in Eastern Nepal

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Authors

BKBasudha KhanalLSLok Bahadur ShresthaASAbhilasha Sharma

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Overview

Retrospective analysis highlights rising antimicrobial resistance in blood pathogens, indicating urgent need for policy changes.

Key Points

  • The study reveals a significant increase in antimicrobial resistance among pathogens in bloodstream infections.
  • Culture positivity rate was 12.1%, with Staphylococcus aureus being the most common organism at 44%.
  • The analysis covered 79,241 blood samples over ten years, utilizing standard microbiological procedures for organism identification.
  • The notable surge in multidrug-resistant and extensively drug-resistant organisms presents a serious challenge for treatment, especially in low-resource settings.

Cite This Study

Khanal et al. (2025) studied this question.

synapsesocial.com/papers/68c24236b210217d647a2e93https://doi.org/10.1186/s12879-025-11413-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Microbiological profile and antimicrobial resistance patterns of bloodstream infections in a tertiary care hospital in eastern India2025
  2. 2Microbial Epidemiology and Antimicrobial Resistance of Bloodstream Infections in Hospitalized Patients During 2019–2023 in Xiangyang, China2025
  3. 3A Retrospective Analysis of Bacterial Infections (2021–2024) in a Reference Laboratory in Kathmandu, Nepal2025
  4. 4Distribution and Antimicrobial Resistance Analysis of Blood Culture Isolates at a Chinese National Cardiovascular Regional Medical Center: A 7-Year Retrospective Study2025
  5. 5Beyond Neutropenia: 14 Years Analysis of bloodstream infections in Hematological malignancies.2025