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September 5, 2025Journal of Infection and Public HealthOpen Access

Beyond Neutropenia: 14 Years Analysis of bloodstream infections in Hematological malignancies.

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Authors

AKAiah M. KhatebABAhmed S. BarefahOROsman Radhwi

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Overview

Retrospective study on bloodstream infections noted high resistance patterns and mortality in hematological malignancies, indicating urgent need for optimized management.

Key Points

  • Fourteen percent of patients with hematological malignancies experienced bloodstream infections, indicating a significant clinical challenge.
  • Among 2,112 patients, bacterial infections were predominant, accounting for 90%, with Gram-negative bacteria such as E. coli being notably high.
  • Statistical analysis revealed concerning resistance patterns, especially in Klebsiella pneumoniae, where mortality reached 100% for resistant strains.
  • Improved diagnostic strategies using both aerobic and anaerobic cultures enhanced identification of polymicrobial infections, suggesting better management potential.

Cite This Study

Khateb et al. (2025) studied this question.

synapsesocial.com/papers/68c239e5b210217d6477db95https://doi.org/10.1016/j.jiph.2025.102948
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