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September 10, 2025Indus journal of bioscience research.Open Access

Comparison of Hypertonic Saline with Normal Saline Nebulization in the Management of Bronchiolitis in Children

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Authors

ARAyesha RiazARAzhar RafiqueMYMuhammad Younas

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Overview

Randomized controlled trial shows hypertonic saline reduces clinical severity score in bronchiolitis better than normal saline.

Key Points

  • Hypertonic saline nebulization leads to greater improvement in clinical severity score compared to normal saline.
  • Median change in clinical severity score after 120 minutes was 3.00 with hypertonic saline versus 2.00 with normal saline.
  • Significant results were observed after 30, 60, and 120 minutes, with a p-value less than 0.05.
  • The study analyzed data from sixty infants enrolled in a randomized controlled trial.

Cite This Study

Riaz et al. (2025) studied this question.

synapsesocial.com/papers/68c241efb210217d647a1fcdhttps://doi.org/10.70749/ijbr.v3i6.2001
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Efficacy of Hypertonic Saline vs Normal Saline + Salbutamol in Treating Acute Bronchiolitis in a Tertiary Care Hospital2025
  2. 2The Efficacy of Nebulized 3% Hypertonic Saline for Acute Bronchiolitis in Infants: A Randomized Controlled Trial2025 · 1 citations
  3. 3A comparative study of nebulized 3% hypertonic saline and normal saline in the management of respiratory syncytial virus-positive acute bronchiolitis in young infants2025
  4. 4Comparison of Mean Length of Hospital Stay in Children with Bronchiolitis Nebulized with 3% Hypertonic Saline with versus without Epinephrine2024
  5. 5A study on the effectiveness of various treatment approaches for bronchiolitis2025