Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025International Journal of Contemporary PediatricsOpen Access

A comparative study of nebulized 3% hypertonic saline and normal saline in the management of respiratory syncytial virus-positive acute bronchiolitis in young infants

View Full Paper
Ask AI
Bookmark
Share

Authors

MKMahmuda KhanomPSProbir Kumar SarkarKSK. M. Ishtiaque Sayeed

Discussion

Loading...

Member takes

Overview

Randomized controlled trial shows hypertonic saline improves clinical outcomes in infants with bronchiolitis, indicating better treatment options.

Key Points

  • Nebulized 3% hypertonic saline significantly improves clinical outcomes in infants with RSV-positive bronchiolitis.
  • The hypertonic saline group had a greater reduction in respiratory distress measured by MRDAI at 12 hours (5.20 vs 5.98).
  • Participants receiving hypertonic saline required shorter oxygen therapy (10.12 hours vs 11.54 hours) and shorter hospital stays (62.98 hours vs 79.64 hours).
  • Incorporating nebulized hypertonic saline into treatment protocols may enhance management strategies for acute bronchiolitis.

Cite This Study

Khanom et al. (2025) studied this question.

synapsesocial.com/papers/68c240deb210217d6479c6a0https://doi.org/10.18203/2349-3291.ijcp20252212
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Efficacy of Nebulized 3% Hypertonic Saline for Acute Bronchiolitis in Infants: A Randomized Controlled Trial2025
  2. 2Efficacy of Hypertonic Saline vs Normal Saline + Salbutamol in Treating Acute Bronchiolitis in a Tertiary Care Hospital2025
  3. 3Comparison of Hypertonic Saline with Normal Saline Nebulization in the Management of Bronchiolitis in Children2025
  4. 4Comparison of Mean Length of Hospital Stay in Children with Bronchiolitis Nebulized with 3% Hypertonic Saline with versus without Epinephrine2024
  5. 5A study on the effectiveness of various treatment approaches for bronchiolitis2025