Evaluation of Oral Corticosteroids in Infants with Acute Bronchiolitis: A Quasi-Experimental Study

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Discussion

Quasi-experimental study assesses clinical efficacy of oral corticosteroids versus placebo in infants, indicating limited benefits.

Clinical improvement was seen in 97.4% of infants receiving corticosteroids, compared to 94.9% in the placebo group, showing no significant difference.
Participants aged 3 months to 2 years were assessed using a validated respiratory distress score after three days of treatment.
Oral prednisolone was administered at 1 mg/kg/dose alongside standard care for mild to moderate bronchiolitis in a total of 234 children.
The findings suggest that routine use of corticosteroids in such cases may not be beneficial, highlighting the need for further research.

Razzaq et al. (2025) studied this question.

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