Randomized controlled trial compares treatment efficacy of single-dose dexamethasone and multidose prednisolone, suggesting both are effective in children with acute asthma exacerbations.
Key Points
Dexamethasone shows higher treatment efficacy at 91.2%, compared to prednisolone's 79.4%, despite no statistical significance.
The dexamethasone group had a better average PRAM score reduction, improving by 3.24 compared to 4.12 in the prednisolone group.
Involved 68 children, aged 4–12 years, with acute asthma exacerbations, split into two groups for treatment comparison.
Potential for improved compliance with single-dose dexamethasone offers a favorable alternative to traditional multidose corticosteroids.