September 10, 2025ACG Case Reports JournalOpen Access

An Extremely Rare Cause of Protein-Losing Enteropathy: Waldenström Macroglobulinemia

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Authors

OSOmar N. SaabCleveland Clinic MAMarwah AlgodiJersey Shore University Medical Center HAHasan Al‐Obaidi

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Implication

Case report reveals hypoproteinemia and elevated IgM levels in protein-losing enteropathy, suggesting Waldenström macroglobulinemia as potential etiology.

Key Points

Waldenström macroglobulinemia can lead to protein-losing enteropathy and should be considered in unexplained cases.
A 66-year-old man presented with abdominal symptoms and experienced significant weight loss over six months.
Biopsy revealed IgM deposition and dilated villi, supporting a diagnosis of Waldenström macroglobulinemia.
Identifying Waldenström macroglobulinemia in PLE cases may improve clinical outcomes and management strategies.

Cite This Study

Saab et al. (2025) studied this question.

synapsesocial.com/papers/68c240deb210217d6479c703 https://doi.org/10.14309/crj.0000000000001800

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Implication

Case report reveals hypoproteinemia and elevated IgM levels in protein-losing enteropathy, suggesting Waldenström macroglobulinemia as potential etiology.

An Extremely Rare Cause of Protein-Losing Enteropathy: Waldenström Macroglobulinemia

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Implication

Key Points

Cite This Study

An Extremely Rare Cause of Protein-Losing Enteropathy: Waldenström Macroglobulinemia

Discussion

Member takes

Implication

Key Points

Cite This Study

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